The Biginelli reaction cardBiginelli reaction

Biginelli reaction

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The Biginelli reaction is a multiple-component chemical reaction that creates 3,4-dihydropyrimidin-2(1H)-ones 4 from ethyl acetoacetate 1, an aryl aldehyde (such as benzaldehyde 2), and urea 3. It is named for the Italian chemist Pietro Biginelli.

Excerpt from the Wikipedia article “Biginelli reaction”, under the CC BY-SA 4.0 license. Read the article on Wikipedia

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