Dihydrofolate reductase

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Science and technology

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What Wikipedia says

Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as an electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in one-carbon transfer chemistry. In humans, the DHFR enzyme is encoded by the DHFR gene.

Excerpt from the Wikipedia article “Dihydrofolate reductase”, under the CC BY-SA 4.0 license. Read the article on Wikipedia

Image: Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute, Public domain, via Wikimedia Commons.