Hurler syndrome

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What Wikipedia says

Hurler syndrome, also known as mucopolysaccharidosis Type IH (MPS-IH), Hurler's disease, and formerly gargoylism, is a genetic disorder that results in the buildup of large sugar molecules called glycosaminoglycans (also called GAGs, formerly mucopolysaccharides) in lysosomes.

Excerpt from the Wikipedia article “Hurler syndrome”, under the CC BY-SA 4.0 license. Read the article on Wikipedia

Image: Sydney S. Gellis and Murray Feingold, Public domain, via Wikimedia Commons.