ATM serine/threonine kinase

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ATM serine/threonine kinase or Ataxia-telangiectasia mutated, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks (canonical pathway), oxidative stress, topoisomerase cleavage complexes, splicing intermediates, R-loops and in some cases by single-strand DNA breaks.

Excerpt from the Wikipedia article “ATM serine/threonine kinase”, under the CC BY-SA 4.0 license. Read the article on Wikipedia

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