First pass effect

Rarity: Uncommon

A topic a little better known than average, read and translated beyond its own country.

Rarity follows how well known the article is: its views on the French and English Wikipedia over a year, and the number of languages it exists in.

At a glance

Class

Notion

Domain

Science and technology

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Nobody has pulled it yet.

What Wikipedia says

The first pass effect (FPE), also known as first-pass metabolism (FPM) or presystemic metabolism, is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

Excerpt from the Wikipedia article “First pass effect”, under the CC BY-SA 4.0 license. Read the article on Wikipedia

Image: Marcelo Reis, CC BY-SA 3.0, via Wikimedia Commons.