Leber's hereditary optic neuropathy

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Leber's hereditary optic neuropathy (LHON) is a mitochondrially inherited (transmitted from mother to offspring) degeneration of retinal ganglion cells (RGCs) and their axons that leads to an acute or subacute loss of central vision; it predominantly affects adult males, and onset is more likely in younger adults.

Excerpt from the Wikipedia article “Leber's hereditary optic neuropathy”, under the CC BY-SA 4.0 license. Read the article on Wikipedia

Image: File:Autosomal dominant - en.svg: Domaina, Angelito7 and SUM1 Derivative work: SUM1, CC BY-SA 4.0, via Wikimedia Commons.